GSK-3 inhibitors induce chromosome instability

<p>Abstract</p> <p>Background</p> <p>Several mechanisms operate during mitosis to ensure accurate chromosome segregation. However, during tumour evolution these mechanisms go awry resulting in chromosome instability. While several lines of evidence suggest that mutation...

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Bibliographic Details
Main Authors: Staples Oliver D, Ray-Sinha Arpita, Tighe Anthony, Taylor Stephen S
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/8/34