Differential activity of candidate microbicides against early steps of HIV-1 infection upon complement virus opsonization

<p>Abstract</p> <p>Background</p> <p>HIV-1 in genital secretions may be opsonized by several molecules including complement components. Opsonized HIV-1 by complement enhances the infection of various mucosal target cells, such as dendritic cells (DC) and epithelial cell...

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Bibliographic Details
Main Authors: Bell Thomas W, Balzarini Jan, Schols Dominique, Bouhlal Hicham, Charpentier Charlotte, Saïdi Héla, Jenabian Mohammad-Ali, Vanham Guido, Bélec Laurent
Format: Article
Language:English
Published: BMC 2010-06-01
Series:AIDS Research and Therapy
Online Access:http://www.aidsrestherapy.com/content/7/1/16