Production of CFTR-ΔF508 Rabbits

Production of CFTR-ΔF508 Rabbits

Cystic Fibrosis (CF) is a lethal autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). The most common mutation is the deletion of phenylalanine residue at position 508 (ΔF508). Here we report the production of CFTR-ΔF508...

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Bibliographic Details
Main Authors: Dongshan Yang, Xiubin Liang, Brooke Pallas, Mark Hoenerhoff, Zhuoying Ren, Renzhi Han, Jifeng Zhang, Y. Eugene Chen, Jian-Ping Jin, Fei Sun, Jie Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
CRISPR/Cas9
cystic fbrosis
CFTR-ΔF508
rabbits
gene edit
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.627666/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.627666/full

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