Optical Imaging of Apoptosis as a Biomarker of Tumor Response to Chemotherapy

A rapid and accurate assessment of the antitumor efficacy of new therapeutic drugs could speed up drug discovery and improve clinical decision making. Based on the hypothesis that most effective antitumor agents induce apoptosis, we developed a near-infrared fluorescent (NIRF) annexin V to be used...

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Bibliographic Details
Main Authors: Eyk A. Schellenberger, Alexei Bogdanov, Jr., Alexander Petrovsky, Vasilis Ntziachristos, Ralph Weissleder, Lee Josephson
Format: Article
Language:English
Published: Elsevier 2003-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558603800507