Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans.

Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans.

Innate immunity in Caenorhabditis elegans requires a conserved PMK-1 p38 mitogen-activated protein kinase (MAPK) pathway that regulates the basal and pathogen-induced expression of immune effectors. The mechanisms by which PMK-1 p38 MAPK regulates the transcriptional activation of the C. elegans imm...

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Bibliographic Details
Main Authors: Robert P Shivers, Daniel J Pagano, Tristan Kooistra, Claire E Richardson, Kirthi C Reddy, Janelle K Whitney, Odile Kamanzi, Kunihiro Matsumoto, Naoki Hisamoto, Dennis H Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2848548?pdf=render

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http://europepmc.org/articles/PMC2848548?pdf=render

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