Decreasing fluconazole susceptibility of clinical South African Cryptococcus neoformans isolates over a decade.

<h4>Background</h4>Fluconazole is used in combination with amphotericin B for induction treatment of cryptococcal meningitis and as monotherapy for consolidation and maintenance treatment. More than 90% of isolates from first episodes of cryptococcal disease had a fluconazole minimum inh...

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Bibliographic Details
Main Authors: Serisha D Naicker, Ruth S Mpembe, Tsidiso G Maphanga, Thokozile G Zulu, Daniel Desanto, Jeannette Wadula, Nomonde Mvelase, Caroline Maluleka, Kessendri Reddy, Halima Dawood, Motlatji Maloba, Nelesh P Govender, for GERMS-SA
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008137