The Genetic Variability of APOE in Different Human Populations and Its Implications for Longevity

The Genetic Variability of APOE in Different Human Populations and Its Implications for Longevity

Human longevity is a complex phenotype resulting from the combinations of context-dependent gene-environment interactions that require analysis as a dynamic process in a cohesive ecological and evolutionary framework. Genome-wide association (GWAS) and whole-genome sequencing (WGS) studies on centen...

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Bibliographic Details
Main Authors: Paolo Abondio, Marco Sazzini, Paolo Garagnani, Alessio Boattini, Daniela Monti, Claudio Franceschi, Donata Luiselli, Cristina Giuliani
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Genes
Subjects:
apolipoprotein E
APOE
longevity
populations
genomics
Online Access:http://www.mdpi.com/2073-4425/10/3/222

Internet

http://www.mdpi.com/2073-4425/10/3/222

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