BRCA1 and BRCA2 mutations in ovarian cancer patients from Belarus: update

Abstract Background Mutations in BRCA1 and BRCA2 are well-established risk factors for breast and ovarian cancer. In Central-Eastern European counties, the founder mutations in the BRCA1 are responsible for a significant proportion of ovarian cancer cases, however, regional differences in the freque...

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Bibliographic Details
Main Authors: Alena Savanevich, Olgierd Ashuryk, Cezary Cybulski, Jan Lubiński, Jacek Gronwald
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:https://doi.org/10.1186/s13053-021-00169-y