Loss of topographic specificity of LTD-like plasticity is a trait marker in focal dystonia

In focal hand dystonia, long-term potentiation (LTP) and depression (LTD)-like neuronal plasticity, as assessed by paired associative stimulation (PAS) targeting the hand-associated motor cortex, is enhanced and the topographic organization of plasticity is lost. However, if any of these abnormaliti...

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Bibliographic Details
Main Authors: David Weise, Axel Schramm, Marcus Beck, Karlheinz Reiners, Joseph Classen
Format: Article
Language:English
Published: Elsevier 2011-05-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110003840