Extracellular Signals of a Human Epithelial Colorectal Adenocarcinoma (Caco-2) Cell Line Facilitate the Penetration of Pseudomonas aeruginosa PAO1 Strain through the Mucin Layer

Extracellular Signals of a Human Epithelial Colorectal Adenocarcinoma (Caco-2) Cell Line Facilitate the Penetration of Pseudomonas aeruginosa PAO1 Strain through the Mucin Layer

Pseudomonas aeruginosa can penetrate the layer of mucus formed by host intestinal epithelial cells, often resulting in sepsis in immunocompromised patients. We have previously demonstrated that P. aeruginosa can penetrate the mucin layer by flagellar motility and the degradation of the mucin layer....

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Bibliographic Details
Main Authors: Naoki Hayashi, Atsushi Yokotani, Masami Yamamoto, Mariko Kososhi, Mayu Morita, Chiaki Fukunishi, Nagisa Nishizawa, Naomasa Gotoh
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Pseudomonas aeruginosa
human colorectal adenocarcinoma cell line
flagellar motility
chemotaxis
translocation
sepsis
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00415/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00415/full

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