Fibrotic myofibroblasts manifest genome-wide derangements of translational control.

BACKGROUND:As a group, fibroproliferative disorders of the lung, liver, kidney, heart, vasculature and integument are common, progressive and refractory to therapy. They can emerge following toxic insults, but are frequently idiopathic. Their enigmatic propensity to resist therapy and progress to or...

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Bibliographic Details
Main Authors: Ola Larsson, Deanna Diebold, Danhua Fan, Mark Peterson, Richard Seonghun Nho, Peter B Bitterman, Craig A Henke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2528966?pdf=render