Inhibitory effect of alpinetin on IL‐6 expression by promoting cytosine methylation in CpG islands in the IL‐6 promoter region

Inhibitory effect of alpinetin on IL‐6 expression by promoting cytosine methylation in CpG islands in the IL‐6 promoter region

Abstract Background Alpinetin is a flavonoid which exerts antibacterial and anti‐inflammatory functions. In order to prove that the induced methylation is an important mechanism for alpinetin in regulating the expression of inflammatory factor Interleukin‐6 (IL‐6), we detected the dinucleotide methy...

Full description

Bibliographic Details
Main Authors: Ke Hu, Yuxian Li, Minghua Liang, Lijing Liu, Yuefu Chen, Minjiang Huang, Bifeng Tan, Yingquan Luo, Huiming Yin
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
Alpinetin
CpG island
IL‐6
methylation
murine macrophage
promoter region
Online Access:https://doi.org/10.1002/mgg3.993

Internet

https://doi.org/10.1002/mgg3.993

Similar Items