Conditional transgenesis using Dimerizable Cre (DiCre).

Cre recombinase is extensively used to engineer the genome of experimental animals. However, its usefulness is still limited by the lack of an efficient temporal control over its activity. We have recently developed a conceptually new approach to regulate Cre recombinase, that we have called Dimeriz...

Full description

Bibliographic Details
Main Authors: Nicolas Jullien, Isabelle Goddard, Samia Selmi-Ruby, Jean-Luc Fina, Harold Cremer, Jean-Paul Herman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2131782?pdf=render