A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion in C. elegans.

The evolutionary fate of an allele ordinarily depends on its contribution to host fitness. Occasionally, however, genetic elements arise that are able to gain a transmission advantage while simultaneously imposing a fitness cost on their hosts. We previously discovered one such element in C. elegans...

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Bibliographic Details
Main Authors: Hannah S Seidel, Michael Ailion, Jialing Li, Alexander van Oudenaarden, Matthew V Rockman, Leonid Kruglyak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3144186?pdf=render