Irinotecan Synergistically Enhances the Antiproliferative and Proapoptotic Effects of Axitinib In Vitro and Improves Its Anticancer Activity In Vivo

Irinotecan Synergistically Enhances the Antiproliferative and Proapoptotic Effects of Axitinib In Vitro and Improves Its Anticancer Activity In Vivo

Aims: To demonstrate the synergistic antiproliferative and proapoptotic activity of irinotecan and axitinib in vitro and the improvement of the in vivo effects on angiogenesis and pancreatic cancer. Methods: Proliferation and apoptotic assays were performed on human dermal microvascular endothelial...

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Bibliographic Details
Main Authors: Bastianina Canu, Anna Fioravanti, Paola Orlandi, Teresa Di Desidero, Greta Alì, Gabriella Fontanini, Antonello Di Paolo, Mario Del Tacca, Romano Danesi, Guido Bocci
Format: Article
Language:English
Published: Elsevier 2011-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800709

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http://www.sciencedirect.com/science/article/pii/S1476558611800709

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