TIM3 expression on TILs is associated with poor response to neoadjuvant chemotherapy in patients with locally advanced triple-negative breast cancer

TIM3 expression on TILs is associated with poor response to neoadjuvant chemotherapy in patients with locally advanced triple-negative breast cancer

Abstract Background The expression of immune checkpoint receptors (ICRs) on tumor-infiltrating lymphocytes (TILs) is associated with better response to immunotherapies via immune checkpoint inhibitors. Therefore, we investigated various ICR expressions on TILs in patients with locally advanced tripl...

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Bibliographic Details
Main Authors: Neslihan Cabioglu, Semen Onder, Gizem Oner, Hüseyin Karatay, Mustafa Tukenmez, Mahmut Muslumanoglu, Abdullah İgci, Yeşim Eralp, Adnan Aydiner, Pınar Saip, Ekrem Yavuz, Vahit Ozmen
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
Triple negative breast cancer
LAG-3
PD1
PDL1
CTLA4
T-cell immunoglobulin
Online Access:https://doi.org/10.1186/s12885-021-08054-6

Internet

https://doi.org/10.1186/s12885-021-08054-6

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