Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro

Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro

Abstract Background Tumor-associated macrophages (TAM) are expanded and exhibit tumor-promoting properties within the tumor microenvironment. Current methods to study TAM have not been replicated across cancer types and often do not include exogenous growth factors from the tumor, a key factor in TA...

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Bibliographic Details
Main Authors: Brooke Benner, Luke Scarberry, Lorena P. Suarez-Kelly, Megan C. Duggan, Amanda R. Campbell, Emily Smith, Gabriella Lapurga, Kallie Jiang, Jonathan P. Butchar, Susheela Tridandapani, John Harrison Howard, Robert A. Baiocchi, Thomas A. Mace, William E. Carson
Format: Article
Language:English
Published: BMJ Publishing Group 2019-05-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Tumor-associated macrophages
In vitro generation
Cancer
Immunotherapy
Online Access:http://link.springer.com/article/10.1186/s40425-019-0622-0

Internet

http://link.springer.com/article/10.1186/s40425-019-0622-0

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