Knockdown of Son, a mouse homologue of the ZTTK syndrome gene, causes neuronal migration defects and dendritic spine abnormalities

Knockdown of Son, a mouse homologue of the ZTTK syndrome gene, causes neuronal migration defects and dendritic spine abnormalities

Abstract Zhu-Tokita-Takenouchi-Kim (ZTTK) syndrome, a rare congenital anomaly syndrome characterized by intellectual disability, brain malformation, facial dysmorphism, musculoskeletal abnormalities, and some visceral malformations is caused by de novo heterozygous mutations of the SON gene. The nuc...

Full description

Bibliographic Details
Main Authors: Masashi Ueda, Tohru Matsuki, Masahide Fukada, Shima Eda, Akie Toya, Akio Iio, Hidenori Tabata, Atsuo Nakayama
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Brain
Subjects:
SON
Zhu-Tokita-Takenouchi-Kim syndrome
Brain malformation
Intellectual disability
Neuronal migration
Spinogenesis
Online Access:http://link.springer.com/article/10.1186/s13041-020-00622-4

Internet

http://link.springer.com/article/10.1186/s13041-020-00622-4

Similar Items