FI-Net: Identification of Cancer Driver Genes by Using Functional Impact Prediction Neural Network

Identification of driver genes, whose mutations cause the development of tumors, is crucial for the improvement of cancer research and precision medicine. To overcome the problem that the traditional frequency-based methods cannot detect lowly recurrently mutated driver genes, researchers have focus...

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Bibliographic Details
Main Authors: Hong Gu, Xiaolu Xu, Pan Qin, Jia Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.564839/full