Deamidated Human Triosephosphate Isomerase is a Promising Druggable Target

Therapeutic strategies for the treatment of any severe disease are based on the discovery and validation of druggable targets. The human genome encodes only 600–1500 targets for small-molecule drugs, but posttranslational modifications lead to a considerably larger druggable proteome. The spontaneou...

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Bibliographic Details
Main Authors: Sergio Enríquez-Flores, Luis Antonio Flores-López, Itzhel García-Torres, Ignacio de la Mora-de la Mora, Nallely Cabrera, Pedro Gutiérrez-Castrellón, Yoalli Martínez-Pérez, Gabriel López-Velázquez
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/7/1050