Two-component signal transduction system CBO0787/CBO0786 represses transcription from botulinum neurotoxin promoters in Clostridium botulinum ATCC 3502.

Blocking neurotransmission, botulinum neurotoxin is the most poisonous biological substance known to mankind. Despite its infamy as the scourge of the food industry, the neurotoxin is increasingly used as a pharmaceutical to treat an expanding range of muscle disorders. Whilst neurotoxin expression...

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Bibliographic Details
Main Authors: Zhen Zhang, Hannu Korkeala, Elias Dahlsten, Elina Sahala, John T Heap, Nigel P Minton, Miia Lindström
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3610760?pdf=render