Development of an OP9 derived cell line as a robust model to rapidly study adipocyte differentiation.

One hallmark of obesity is adipocyte hypertrophy and hyperplasia. To gain novel insights into adipose biology and therapeutics, there is a pressing need for a robust, rapid, and informative cell model of adipocyte differentiation for potential RNAi and drug screens. Current models are prohibitive fo...

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Bibliographic Details
Main Authors: Jacqueline M Lane, Jamie R Doyle, Jean-Philippe Fortin, Alan S Kopin, José M Ordovás
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4237323?pdf=render