Formulation, high throughput in vitro screening and in vivo functional characterization of nanoemulsion-based intranasal vaccine adjuvants.

Formulation, high throughput in vitro screening and in vivo functional characterization of nanoemulsion-based intranasal vaccine adjuvants.

Vaccine adjuvants have been reported to induce both mucosal and systemic immunity when applied to mucosal surfaces and this dual response appears important for protection against certain pathogens. Despite the potential advantages, however, no mucosal adjuvants are currently approved for human use....

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Bibliographic Details
Main Authors: Pamela T Wong, Pascale R Leroueil, Douglas M Smith, Susan Ciotti, Anna U Bielinska, Katarzyna W Janczak, Catherine H Mullen, Jeffrey V Groom, Erin M Taylor, Crystal Passmore, Paul E Makidon, Jessica J O'Konek, Andrzej Myc, Tarek Hamouda, James R Baker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4427474?pdf=render

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http://europepmc.org/articles/PMC4427474?pdf=render

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