A computational model of a microfluidic device to measure the dynamics of oxygen-dependent ATP release from erythrocytes.

Erythrocytes are proposed to be involved in blood flow regulation through both shear- and oxygen-dependent mechanisms for the release of adenosine triphosphate (ATP), a potent vasodilator. In a recent study, the dynamics of shear-dependent ATP release from erythrocytes was measured using a microflui...

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Bibliographic Details
Main Authors: Richard J Sove, Nour Ghonaim, Daniel Goldman, Christopher Gerald Ellis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3842322?pdf=render