A novel Bcl-2 inhibitor, BM-1197, induces apoptosis in malignant lymphoma cells through the endogenous apoptotic pathway

Abstract Background Bcl-2 family members play an important role in the development of malignant lymphoma and can induce drug resistance in anticancer treatment. The development of small molecules targeting Bcl-2 family proteins may be a new strategy for the treatment of malignant lymphoma. In this s...

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Bibliographic Details
Main Authors: Yue-Li Sun, Wen-Qi Jiang, Qiu-Yun Luo, Da-Jun Yang, Yu-Chen Cai, Hui-Qiang Huang, Jian Sun
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-019-6169-0