HMGB1: A Promising Therapeutic Target for Prostate Cancer

High mobility group box 1 (HMGB1) was originally discovered as a chromatin-binding protein several decades ago. It is now increasingly evident that HMGB1 plays a major role in several disease conditions such as atherosclerosis, diabetes, arthritis, sepsis, and cancer. It is intriguing how deregulati...

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Bibliographic Details
Main Authors: Munirathinam Gnanasekar, Ramaswamy Kalyanasundaram, Guoxing Zheng, Aoshuang Chen, Maarten C. Bosland, André Kajdacsy-Balla
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/2013/157103