Non-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in mice.

Non-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in mice.

Myeloid differentiation factor 88 (MyD88) and MyD88-adaptor like (Mal)/Toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) play a critical role in transducing signals downstream of the Toll-like receptor (TLR) family. While genetic ablation of the TLR4/MyD88 signaling axis in mice...

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Bibliographic Details
Main Authors: Saleela M Ruwanpura, Louise McLeod, Andrew R Lilja, Gavin Brooks, Lovisa F Dousha, Huei J Seow, Steven Bozinovski, Ross Vlahos, Paul J Hertzog, Gary P Anderson, Brendan J Jenkins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3812132?pdf=render

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http://europepmc.org/articles/PMC3812132?pdf=render

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