Cholesterol and stroke: role of PCSK9 inhibitors
Introduction: Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays an important role in the modulation of plasma levels of low density lipoprotein cholesterol (LDLC). PCSK9 binds to the LDL receptor (LDLR), disrupts its endocytic recycling itinerary and directs it to lysosomal degradation. Ac...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier España
2019-04-01
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| Series: | Neurología (English Edition) |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2173580819300148 |