Altered Sexual Behavior in Dopamine Transporter (DAT) Knockout Male Rats: A Behavioral, Neurochemical and Intracerebral Microdialysis Study

Altered Sexual Behavior in Dopamine Transporter (DAT) Knockout Male Rats: A Behavioral, Neurochemical and Intracerebral Microdialysis Study

Central dopamine plays a key role in sexual behavior. Recently, a Dopamine Transporter knockout (DAT KO) rat has been developed, which displays several behavioral dysfunctions that have been related to increased extracellular dopamine levels and altered dopamine turnover secondary to DAT gene silenc...

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Bibliographic Details
Main Authors: Fabrizio Sanna, Jessica Bratzu, Maria Pina Serra, Damiana Leo, Marina Quartu, Marianna Boi, Stefano Espinoza, Raul R. Gainetdinov, Maria Rosaria Melis, Antonio Argiolas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
sexual behavior
DAT knockout rats
dopamine
glutamic acid
D-FosB
BDNF/trkB
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2020.00058/full

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https://www.frontiersin.org/article/10.3389/fnbeh.2020.00058/full

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