XBP1 negatively regulates CENPF expression via recruiting ATF6α to the promoter during ER stress

Abstract Background Centromere protein F (CENPF) is a key component of the kinetochore complex involved in mitosis, cell differentiation and cellular response to stresses. However, the alteration of CENPF in response to endoplasmic reticulum (ER) stress has not been well described. In the present st...

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Bibliographic Details
Main Authors: Tao Shen, Yan Li, Shuang Liang, Zhiguang Chen
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-020-01553-9