An ELISA assay using a combination of recombinant proteins from multiple strains of Orientia tsutsugamushi offers an accurate diagnosis for scrub typhus

Abstract Background Scrub typhus (ST) is a disease caused by an obligate intracellular bacterium, Orientia tsutsugamushi, an organism that requires a BSL3 laboratory for propagation. The disease is hallmarked by an eschar at the site of the chigger bite, followed by the development of fever, malaise...

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Main Authors: Chien-Chung Chao, Zhiwen Zhang, Tatyana Belinskaya, Wilawan Thipmontree, Wiwit Tantibhedyangkul, Saowaluk Silpasakorn, Ekkarat Wongsawat, Yupin Suputtamongkol, Wei-Mei Ching
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Infectious Diseases
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12879-017-2512-8