p58IPK Is an Endogenous Neuroprotectant for Retinal Ganglion Cells

p58IPK is an endoplasmic reticulum (ER)-resident chaperone playing a critical role in facilitating protein folding and protein homeostasis. Previously, we have demonstrated that p58IPK is expressed broadly in retinal neurons including retinal ganglion cells (RGCs) and loss of p58IPK results in age-r...

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Bibliographic Details
Main Authors: Todd McLaughlin, Narayan Dhimal, Junhua Li, Joshua Jianxin Wang, Sarah Xin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00267/full