Interplay between basic residues of hepatitis C virus glycoprotein E2 with viral receptors, neutralizing antibodies and lipoproteins.

Interplay between basic residues of hepatitis C virus glycoprotein E2 with viral receptors, neutralizing antibodies and lipoproteins.

Positively-charged amino acids are located at specific positions in the envelope glycoprotein E2 of the hepatitis C virus (HCV): two histidines (H) and four arginines (R) in two conserved WHY and one RGERCDLEDRDR motifs, respectively. Additionally, the E2 hypervariable region 1 (HVR1) is rich in bas...

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Bibliographic Details
Main Authors: George Koutsoudakis, Jakub Dragun, Sofia Pérez-Del-Pulgar, Mairene Coto-Llerena, Laura Mensa, Gonzalo Crespo, Patricia González, Miquel Navasa, Xavier Forns
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23300734/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23300734/?tool=EBI

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