GSK-3 and CK2 Kinases Converge on Timeless to Regulate the Master Clock

The molecular clock relies on a delayed negative feedback loop of transcriptional regulation to generate oscillating gene expression. Although the principal components of the clock are present in all circadian neurons, different neuronal clusters have varying effects on rhythmic behavior, suggesting...

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Bibliographic Details
Main Authors: Deniz Top, Emily Harms, Sheyum Syed, Eliza L. Adams, Lino Saez
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716307240