Detection of genetically altered copper levels in Drosophila tissues by synchrotron x-ray fluorescence microscopy.

Tissue-specific manipulation of known copper transport genes in Drosophila tissues results in phenotypes that are presumably due to an alteration in copper levels in the targeted cells. However direct confirmation of this has to date been technically challenging. Measures of cellular copper content...

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Bibliographic Details
Main Authors: Jessica C Lye, Joab E C Hwang, David Paterson, Martin D de Jonge, Daryl L Howard, Richard Burke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3203902?pdf=render