GIT1 regulates synaptic structural plasticity underlying learning.

The signaling scaffold protein GIT1 is expressed widely throughout the brain, but its function in vivo remains elusive. Mice lacking GIT1 have been proposed as a model for attention deficit-hyperactivity disorder, due to alterations in basal locomotor activity as well as paradoxical locomotor suppre...

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Bibliographic Details
Main Authors: Amanda C Martyn, Krisztian Toth, Robert Schmalzigaug, Nathan G Hedrick, Ramona M Rodriguiz, Ryohei Yasuda, William C Wetsel, Richard T Premont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5858814?pdf=render