Necl-4/SynCAM-4 is expressed in myelinating oligodendrocytes but not required for axonal myelination.

The timing and progression of axonal myelination are precisely controlled by intercellular interactions between neurons and glia in development. Previous in vitro studies demonstrated that Nectin like 4 (Necl-4, also known as cell adhesion molecule Cadm-4 or SynCAM-4) plays an essential role in axon...

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Bibliographic Details
Main Authors: Ying Zhu, Hong Li, Kehan Li, Xiaofeng Zhao, Tai An, Xuemei Hu, Jinsil Park, Hao Huang, Yin Bin, Boqin Qiang, Jiangang Yuan, Xiaozhong Peng, Mengsheng Qiu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3659047?pdf=render