Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis[S]

The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin has been implicated in adipocyte differentiation, lipid droplet (LD) formation, and motor neuron development. However, the molecular function of seipin and its disease-causing mutants remains to be elucidated. H...

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Bibliographic Details
Main Authors: Weihua Fei, Hui Li, Guanghou Shui, Tamar S. Kapterian, Christopher Bielby, Ximing Du, Andrew J. Brown, Peng Li, Markus R. Wenk, Pingsheng Liu, Hongyuan Yang
Format: Article
Language:English
Published: Elsevier 2011-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408181