Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling

Morphogen signaling proteins disperse across tissues to activate signal transduction in target cells. We investigated dispersion of Hedgehog (Hh), Wnt homolog Wingless (Wg), and Bone morphogenic protein homolog Decapentaplegic (Dpp) in the Drosophila wing imaginal disc. We discovered that delivery o...

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Bibliographic Details
Main Authors: Ryo Hatori, Brent M Wood, Guilherme Oliveira Barbosa, Thomas B Kornberg
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/71744