Evaluation of Enoyl-Acyl Carrier Protein Reductase Inhibitors as Pseudomonas aeruginosa Quorum-Quenching Reagents

Pseudomonas aeruginosa is an opportunistic pathogen which is responsible for a wide range of infections. Production of virulence factors and biofilm formation by P. aeruginosa are partly regulated by cell-to-cell communication quorum-sensing systems. Identification of quorum-quenching reagents which...

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Bibliographic Details
Main Authors: Søren Molin, Claus Sternberg, Yang Liu, Liang Yang
Format: Article
Language:English
Published: MDPI AG 2010-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/2/780/