Donor-derived Cell-free DNA Identifies Antibody-mediated Rejection in Donor Specific Antibody Positive Kidney Transplant Recipients

Donor-derived Cell-free DNA Identifies Antibody-mediated Rejection in Donor Specific Antibody Positive Kidney Transplant Recipients

Background. Elevated levels of donor-derived cell-free DNA (dd-cfDNA) in the plasma of renal allograft recipients indicates organ injury and an increased probability of active rejection. Donor-specific antibodies (DSA) to HLA antigens are associated with risk of antibody-mediated rejection (ABMR). T...

Full description

Bibliographic Details
Main Authors: Stanley C. Jordan, MD, FASN, FAST, Suphamai Bunnapradist, MD, Jonathan S. Bromberg, MD, PhD, Anthony J. Langone, MD, David Hiller, PhD, James P. Yee, MD, PhD, John J. Sninsky, PhD, Robert N. Woodward, PhD, Arthur J. Matas, MD
Format: Article
Language:English
Published: Wolters Kluwer 2018-09-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000000821

Internet

http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000000821

Similar Items