Acute Endoplasmic Reticulum Stress-Independent Unconventional Splicing of XBP1 mRNA in the Nucleus of Mammalian Cells

Acute Endoplasmic Reticulum Stress-Independent Unconventional Splicing of XBP1 mRNA in the Nucleus of Mammalian Cells

The regulation of expression of X-box-binding protein-1 (XBP1), a transcriptional factor, involves an unconventional mRNA splicing that removes the 26 nucleotides intron. In contrast to the conventional splicing that exclusively takes place in the nucleus, determining the location of unconventional...

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Bibliographic Details
Main Authors: Yuanyuan Wang, Pan Xing, Wenjing Cui, Wenwen Wang, Yanfen Cui, Guoguang Ying, Xin Wang, Binghui Li
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:International Journal of Molecular Sciences
Subjects:
ER stress
XBP1
unconventional splicing
unfolded protein response
IRE1α
Online Access:http://www.mdpi.com/1422-0067/16/6/13302

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http://www.mdpi.com/1422-0067/16/6/13302

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