Improving adenoviral vectors and strategies for prostate cancer gene therapy

Gene therapy has been evaluated for the treatment of prostate cancer and includes the application of adenoviral vectors encoding a suicide gene or oncolytic adenoviruses that may be armed with a functional transgene. In parallel, versions of adenoviral vector expressing the p53 gene (Ad-p53) have be...

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Bibliographic Details
Main Authors: Rodrigo Esaki Tamura, Igor Vieira de Luna, Marlous Gomes Lana, Bryan E. Strauss
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2018-08-01
Series:Clinics
Subjects:
p53
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000200309&lng=en&tlng=en