Fetal radiation exposure induces testicular cancer in genetically susceptible mice.

The prevalence of testicular germ cell tumors (TGCT), a common solid tissue malignancy in young men, has been annually increasing at an alarming rate of 3%. Since the majority of testicular cancers are derived from germ cells at the stage of transformation of primordial germ cell (PGC) into gonocyte...

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Bibliographic Details
Main Authors: Gunapala Shetty, Paul B Comish, Connie C Y Weng, Angabin Matin, Marvin L Meistrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3278464?pdf=render