COOLAIR Antisense RNAs Form Evolutionarily Conserved Elaborate Secondary Structures

COOLAIR Antisense RNAs Form Evolutionarily Conserved Elaborate Secondary Structures

There is considerable debate about the functionality of long non-coding RNAs (lncRNAs). Lack of sequence conservation has been used to argue against functional relevance. We investigated antisense lncRNAs, called COOLAIR, at the A. thaliana FLC locus and experimentally determined their secondary str...

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Bibliographic Details
Main Authors: Emily J. Hawkes, Scott P. Hennelly, Irina V. Novikova, Judith A. Irwin, Caroline Dean, Karissa Y. Sanbonmatsu
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Cell Reports
Subjects:
RNA structure
antisense transcripts
COOLAIR
FLC
chemical probing
A. thaliana
evolution
shotgun secondary structure (3S)
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716311159

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http://www.sciencedirect.com/science/article/pii/S2211124716311159

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