Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis

<p>Abstract</p> <p>Background</p> <p>An altered susceptibility of lung fibroblasts to Fas-induced apoptosis has been implicated in the pathogenesis of pulmonary fibrosis; however, the underlying mechanism is not completely understood. Here, we studied the susceptibility...

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Bibliographic Details
Main Authors: Wiesner Olaf, Röcken Christoph, Wille Aline, Bühling Frank, Baier Anja, Meinecke Ingmar, Welte Tobias, Pap Thomas
Format: Article
Language:English
Published: BMC 2005-04-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/6/1/37