Novel malaria antigen Plasmodium yoelii E140 induces antibody-mediated sterile protection in mice against malaria challenge.

Novel malaria antigen Plasmodium yoelii E140 induces antibody-mediated sterile protection in mice against malaria challenge.

Only a small fraction of the antigens expressed by malaria parasites have been evaluated as vaccine candidates. A successful malaria subunit vaccine will likely require multiple antigenic targets to achieve broad protection with high protective efficacy. Here we describe protective efficacy of a nov...

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Bibliographic Details
Main Authors: Emily C Smith, Keith J Limbach, Nonenipha Rangel, Kyosuke Oda, Jessica S Bolton, Mengyan Du, Kalpana Gowda, Jianyang Wang, J Kathleen Moch, Sharvari Sonawane, Rachel Velasco, Arnel Belmonte, Rebecca Danner, Joanne M Lumsden, Noelle B Patterson, Martha Sedegah, Michael R Hollingdale, Thomas L Richie, John B Sacci, Eileen D Villasante, Joao C Aguiar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232234

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https://doi.org/10.1371/journal.pone.0232234

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