Enhanced Susceptibility of ADAP-Deficient Mice to Listeria monocytogenes Infection Is Associated With an Altered Phagocyte Phenotype and Function

Enhanced Susceptibility of ADAP-Deficient Mice to Listeria monocytogenes Infection Is Associated With an Altered Phagocyte Phenotype and Function

The adhesion and degranulation-promoting adaptor protein (ADAP) serves as a multifunctional scaffold and is involved in the formation of immune signaling complexes. To date, only limited data exist regarding the role of ADAP in pathogen-specific immunity during in vivo infection, and its contributio...

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Bibliographic Details
Main Authors: Martha A. L. Böning, Gerald P. Parzmair, Andreas Jeron, Henning P. Düsedau, Olivia Kershaw, Baolin Xu, Borna Relja, Dirk Schlüter, Ildiko Rita Dunay, Annegret Reinhold, Burkhart Schraven, Dunja Bruder
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
ADAP
adaptor protein
Listeria monocytogenes
neutrophils
inflammatory monocytes
phagocytosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.724855/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.724855/full

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