Upregulation of Small Ubiquitin-Like Modifier 2 and Protein SUMOylation as a Cardioprotective Mechanism Against Myocardial Ischemia-Reperfusion Injury

Upregulation of Small Ubiquitin-Like Modifier 2 and Protein SUMOylation as a Cardioprotective Mechanism Against Myocardial Ischemia-Reperfusion Injury

Background: Small ubiquitin-like modifier (SUMO) proteins modify proteins through SUMOylation as an essential protein post-translational modification (PTM) for regulating redox status, inflammation, and cardiac fibrosis in myocardial infarction. This study aimed to investigate whether natural produc...

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Bibliographic Details
Main Authors: Wei Zhao, Jia Zhao, Xiuying Zhang, Ni Fan, Jianhui Rong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
puerarin
myocardial ischemia/reperfusion injury
SUMO2
sumoylation
ERK
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.731980/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.731980/full

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