Inhibition of Rho-kinase improves response to deep inspiration in ovalbumin-sensitized guinea pigs

Objective(s): The modulatory effect of deep inspiration (DI) on airway constriction is impaired in asthma. However, mechanisms underlying this impairment are not clear. Since there is evidence indicating that Rho-kinase activation mediates force maintenance under oscillatory strain, we investigated...

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Bibliographic Details
Main Authors: Saeed Pazhoohan, Ehsan Aref, Leila Zare, Samaneh Dehghan, Mohammad Javan, Sohrab Hajizadeh, Mohammad Reza Rauofy
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-12-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_16820_3d0cd06240c2380e6418afeabeef5553.pdf